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Wissenschaft
How GLP-1 medications work – in plain language
Semaglutide and tirzepatide mimic hormones that regulate satiety. Here's what actually happens in the body.
by instafit Team
Editorial team · 6 min Reading time
GLP-1 (glucagon-like peptide-1) is a hormone released in the gut after every meal. It signals satiety to the brain, slows gastric emptying and regulates blood sugar.
Modern compounds like semaglutide are synthetic GLP-1 analogues that amplify and prolong this natural effect. Tirzepatide additionally acts on the GIP receptor – a combination that produces particularly pronounced weight reduction in studies.
Important: these medications aren't a 'slimming pill'. They only work when therapy is medically supervised, individually dosed and combined with nutrition and movement.
